Description
=============================================================
Click here to read more : Technical note: IVD material – Antibody and Protein
=============================================================
Any question, please contact: hxinfo@helixarbio.com
BioBench developped a series of clinical-qualified materials for IVD companies, as well as for lifesciences research. These materials including antibody pairs and purified antigens.
Ferritin (or named: Ferritin light chain, FTL) is a universal intracellular protein that stores iron and releases it in a controlled fashion. The protein is produced by almost all living organisms, including archaea, bacteria, algae, higher plants, and animals. It is the primary intracellular iron-storage protein in both prokaryotes and eukaryotes, keeping iron in a soluble and non-toxic form. In humans, it acts as a buffer against iron deficiency and iron overload.
Ferritin is found in most tissues as a cytosolic protein, but small amounts are secreted into the serum where it functions as an iron carrier. Plasma ferritin is also an indirect marker of the total amount of iron stored in the body; hence, serum ferritin is used as a diagnostic test for iron-deficiency anemia. Aggregated ferritin transforms into a toxic form of iron called hemosiderin.
Related Products and Application Suggestion
Product type |
Product name |
Catalog No. |
Host |
Antibody type |
Clone number |
Antibody pairing* / Protein usage |
Advised IVD platform** |
Protein/Antigen |
Human Ferritin |
CP0045 |
293T stable cell line expressed |
\ |
N/A |
Positive control, protein standard, reference substance |
All |
Monoclonal antibody |
Anti Human Ferritin, Mouse mAb, 01 |
MAB0336 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
01 |
Capture Ab: clone 01 - Detection Ab: clone 02 Capture Ab: clone 01 - Detection Ab: clone 04 |
POCT |
Monoclonal antibody |
Anti Human Ferritin, Mouse mAb, 02 |
MAB0337 |
Mouse hybridoma |
Monoclonal antibody, Ig2a |
02 |
Capture Ab: clone 01 Detection Ab: clone 02 |
|
Monoclonal antibody |
Anti Human Ferritin, Mouse mAb, 04 |
MAB0338 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
04 |
Capture Ab: clone 01 Detection Ab: clone 04 |
|
Monoclonal antibody |
Anti Human Ferritin, Mouse mAb, 31 |
MAB0339 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
31 |
Capture Ab: clone 31 Detection Ab: clone 32 |
CLIA |
Monoclonal antibody |
Anti Human Ferritin, Mouse mAb, 32 |
MAB0340 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
32 |
Capture Ab: clone 31 Detection Ab: clone 32 |
|
Note: * Please test the usage of antibody pairs according to your own assay/method/platform/reagent. The listed data were tested in-house by BioBench and only shown as advice. ** Adapted platforms were tested in-house by Bio Bench and only shown as advise. Different assay/method/platform/reagent may lead to different performance of the antibody and protein. |
Human Ferritin Antibody pair suggestion, performance and application suggestion
Tested Platform / Method |
Coating Antibody |
Detection Antibody |
BioBench Comment on Test Result |
LOD / Sensitivity |
Antigen Linearity Range |
POCT |
Clone 01 |
Clone 02 |
***** |
≤ 2 ng/mL |
5 – 500 ng/mL |
Clone 01 |
Clone 04 |
**** |
≤ 3 ng/L |
5 – 500 ng/mL |
|
CLIA |
Clone 31 |
Clone 32 |
***** |
≤ 0.2 ng/mL |
1 – 1,000 ng/mL |
These results were tested in-house by BioBench with limited selection of assay/platform/method/instrument/reagents. Please test the performance in your lab to confirm the performance. |